GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7267979 | 1 | rs6050598 | chr20:25397257 | FAM182A | chr20:26035250-26067552:+ | -0.18 | -3.43 | 0.000654 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050598 | chr20:25397257 | FAM182B | chr20:25744102-25848786:- | 0.26 | 5.41 | 9.89E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050598 | chr20:25397257 | NINL | chr20:25433338-25566153:- | -0.34 | -7.02 | 7.59E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050598 | chr20:25397257 | PYGB | chr20:25228706-25278647:+ | -0.16 | -4.12 | 4.51E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050599 | chr20:25400240 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.43 | 5.2E-13 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050599 | chr20:25400240 | FAM182A | chr20:26035250-26067552:+ | 0.18 | 3.44 | 0.000637 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050599 | chr20:25400240 | FAM182B | chr20:25744102-25848786:- | -0.25 | -5.26 | 2.22E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050599 | chr20:25400240 | NINL | chr20:25433338-25566153:- | 0.34 | 7.1 | 4.42E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050599 | chr20:25400240 | PYGB | chr20:25228706-25278647:+ | 0.15 | 3.79 | 0.000167 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050602 | chr20:25401203 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.43 | 5.2E-13 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050602 | chr20:25401203 | FAM182A | chr20:26035250-26067552:+ | 0.18 | 3.44 | 0.000637 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050602 | chr20:25401203 | FAM182B | chr20:25744102-25848786:- | -0.25 | -5.26 | 2.22E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050602 | chr20:25401203 | NINL | chr20:25433338-25566153:- | 0.34 | 7.1 | 4.42E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050602 | chr20:25401203 | PYGB | chr20:25228706-25278647:+ | 0.15 | 3.79 | 0.000167 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs6050609 | chr20:25411751 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.43 | 5.05E-13 | Liver enzyme levels (alkaline phosphatase) |